In Santiago: Panamericano Hotel is located in Santiago Center, a 3-minute walk to Palacio de la Moneda, 2 minutes to Plaza de la Constitucion, 6 minutes to Santiago Town Square, former National Congress is 3 minutes away, and approximately 3 minutes to the Museum of Chilean Precolombian Art.

The hotel features 200 cozy and spacious non-smoking rooms and suites; all are soundproofed and feature modern décor, free Wi-Fi, air conditioning and heating, TV with cable channels, DVD player, minibar, room service, private bathroom, free toiletries, hair dryer, in-room safe, phone and daily maid service.

Other amenities include free breakfast, elevators, ironing service, laundry, dry cleaning, 24-hour front desk, concierge service, tour desk, ticket service, currency exchange, safe deposit box, luggage storage, guarded parking, gym, spa, and boxing school for executives, airport shuttle (surcharge), shuttle service (surcharge), car hire and free self-parking nearby.